The Substance
2024·2h 21m·Released
7.1
HorrorScience Fiction
“Have you ever dreamt of a better version of yourself?”
A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.
Watch TrailerCast
Demi Moore
Elisabeth
Margaret Qualley
Sue
Dennis Quaid
Harvey
Edward Hamilton-Clark
Fred
Gore Abrams
Oliver
Oscar Lesage
Troy
Christian Erickson
Man at Diner
Robin Greer
Male Nurse
Tom Morton
Doctor
Hugo Diego Garcia
Diego - Boyfriend
Daniel Knight
Casting Director
Jonathon Carley
Assistant Casting Director
Jiselle Henderkott
Girl Auditioning / New Year's Eve Show Dancer
Akil Wingate
TV Host
